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Peptide record

TPDB13552

Antibacterial Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB13552
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
IAGKIAKIAGKIAKIAGKIAKIAGKIA
Physicochemical Analysis
C122H226N34O28
RNDCEQHLMFPSTWYV
AI
2617.35
11.29
7
0
16
+7
3.13
0.796
145.19
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
8
I
0
L
7
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 8 L: 0 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C122H226N34O28
2617.35
11.29
+7
3.13
0.796
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 1 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Terminal Charges Modulate the Pore Forming Activity of Cationic Amphipathic Helices. | Biochim Biophys Acta | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis