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Peptide record

TPDB13543

Antibacterial Antifungal Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB13543
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SLWGKLKEMLAAAGKAVANAVNGLANQ
Physicochemical Analysis
C120H201N35O35S1
RDCHIFPTY
A
2726.19
10.32
3
1
15
+2
1.62
0.222
105.19
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
201.75
5
Residue Composition
number
7
A
0
R
3
N
0
D
0
C
1
E
1
Q
3
G
0
H
0
I
4
L
3
K
1
M
0
F
0
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 0 L: 4 K: 3 M: 1 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
27
C120H201N35O35S1
2726.19
10.32
+2
1.62
0.222
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
21.53 µM
Hemolytic Cytotoxic
10% Hemolysis | 21.53 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Identification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC from the Skin Secretion of the Red-Eyed Tree Frog Agalychnis callidryas. | Antibiotics (Basel) | 2020
Evidence 2 Activity

Activity

40% Hemolysis
Toxicity
45 µM
Hemolytic Cytotoxic
40% Hemolysis | 45 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Identification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC from the Skin Secretion of the Red-Eyed Tree Frog Agalychnis callidryas. | Antibiotics (Basel) | 2020
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis