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Peptide record

TPDB13542

Antibacterial Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB13542
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GEFAQFEQEAQSLEQELSQLEQQLESL
Physicochemical Analysis
C135H208N34O52
RNDCHIKMPTWYV
EQ
3139.33
2.82
0
7
9
-7
13.20
-0.874
79.63
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
10
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
7
E
7
Q
1
G
0
H
0
I
5
L
0
K
0
M
2
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 7 Q: 7 G: 1 H: 0 I: 0 L: 5 K: 0 M: 0 F: 2 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C135H208N34O52
3139.33
2.82
-7
13.20
-0.874
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>>250 µM
Hemolytic Cytotoxic
50% Hemolysis | >>250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-antimicrobial Peptides: Folding-Mediated Host Defense Antagonists | J Biol Chem | 2013