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Peptide record

TPDB13536

Antibacterial Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB13536
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKGKSFKQLHIIVHLVKSWLRTILTHI
Physicochemical Analysis
C153H255N43O33
ANDCEMPY
K
3224.98
11.85
9
0
12
+6
3.45
0.111
137.04
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
170.54
5
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
1
G
3
H
4
I
4
L
5
K
0
M
1
F
0
P
2
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 3 I: 4 L: 4 K: 5 M: 0 F: 1 P: 0 S: 2 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
27
C153H255N43O33
3224.98
11.85
+6
3.45
0.111
Evidence Records 1 records
Evidence 1 Activity

Activity

99.8% Killing
Toxicity
79.6 µM
Cytotoxic
99.8% Killing | 79.6 | µM | target cell: Mouse fibroblasts McCoy

Target

Mouse fibroblasts McCoy

Source & Reference

NA
DBAASP
The Hirudo Medicinalis Microbiome Is a Source of New Antimicrobial Peptides. | Int J Mol Sci | 2020