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Peptide record

TPDB13530

Antibacterial Anticancer Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13530
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RVKRVWYLVIRTVIAGYNLPRAIKKK
Physicochemical Analysis
C148H250N44O31
DCEQHMFS
RKV
3141.89
12.01
8
0
14
+8
2.38
-0.069
127.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
269.90
4
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
4
K
0
M
0
F
1
P
0
S
1
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 4 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 4
Chemical Descriptors
26
C148H250N44O31
3141.89
12.01
+8
2.38
-0.069
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving Cell Selectivity of Fowlicidin-1 by Swapping Residues between Pro-7 and Tyr-20 | Bull Korean Chem Soc | 2019