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Peptide record

TPDB13525

Antibacterial Antiparasitic Hemolysis Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13525
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, PD_Hemolysis, and other sources, with an available 3D structural model.
Sequence
IDWKKVDWKKVSKKTSKVMLKASKFL
Physicochemical Analysis
C147H245N37O35S1
RNCEQGHPY
K
3122.85
10.82
9
2
11
+7
5.45
-0.608
82.31
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
11000
352.24
4
Residue Composition
number
1
A
0
R
0
N
2
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
9
K
1
M
1
F
0
P
3
S
1
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 9 M: 1 F: 1 P: 0 S: 3 T: 1 W: 2 Y: 0 V: 3
Chemical Descriptors
26
C147H245N37O35S1
3122.85
10.82
+7
5.45
-0.608
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Killing
Toxicity
>20 µM
Cytotoxic
50% Killing | >20 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>20 µM
Hemolytic Cytotoxic
50% Hemolysis | >20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis