Back to search

Peptide record

TPDB13524

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13524
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GAVVDILKGAGKNLLSLALNKLSEKV
Physicochemical Analysis
C119H212N32O35
RCQHMFPTWY
L
2651.19
10.16
4
2
13
+2
4.37
0.496
150.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
0
R
2
N
1
D
0
C
1
E
0
Q
3
G
0
H
1
I
6
L
4
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 6 K: 4 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
26
C119H212N32O35
2651.19
10.16
+2
4.37
0.496
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
62.5 µM

Target

Escherichia coli ATCC 35218

Source & Reference

NA

Other

Weakly active against E. coli ATCC 35218 (MIC 62.5 uM), but NOT antibiotic-resistant K.pneumoniae ATCC BAA-2814 (MIC >125 uM) and reference stra
Evidence 2 Activity

Activity

MIC
Antibacterial
>125 µM

Target

K.pneumoniae ATCC BAA-2814

Source & Reference

NA

Other

Weakly active against E. coli ATCC 35218 (MIC 62.5 uM), but NOT antibiotic-resistant K.pneumoniae ATCC BAA-2814 (MIC >125 uM) and reference strains of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (
Evidence 3 Activity

Activity

MIC
Antibacterial
125 µM

Target

K.pneumoniae ATCC 49472

Source & Reference

NA

Other

OT antibiotic-resistant K.pneumoniae ATCC BAA-2814 (MIC >125 uM) and reference strains of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 2
Evidence 4 Activity

Activity

MIC
Antibacterial
250 µM

Target

S.typhimurium ATCC 14028

Source & Reference

NA

Other

TCC BAA-2814 (MIC >125 uM) and reference strains of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 250 uM) and E.faecium ATCC 19434 (MIC 25
Evidence 5 Activity

Activity

MIC
Antibacterial
250 µM

Target

S.aureus ATCC 12600 or ATCC BAA-2312

Source & Reference

NA

Other

ins of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 250 uM) and E.faecium ATCC 19434 (MIC 250 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
250 µM

Target

E.faecium ATCC 19434

Source & Reference

NA

Other

rium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 250 uM) and E.faecium ATCC 19434 (MIC 250 uM).
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
>500 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >500 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Peptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity. | Antibiotics (Basel) | 2020