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Peptide record

TPDB13521

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13521
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGAVLKVLTTGLPAAISWIKRKRQQ
Physicochemical Analysis
C128H222N38O32
NDCEHMFY
AGILK
2805.41
12.43
5
0
12
+5
1.81
0.196
123.85
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
196.05
5
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
3
I
3
L
3
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 3 L: 3 K: 3 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C128H222N38O32
2805.41
12.43
+5
1.81
0.196
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
7.5 µM
Hemolytic Cytotoxic
0% Hemolysis | 7.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cell-selective lysis by novel analogues of melittin against human red blood cells and Escherichia coli. | Biochemistry | 2010