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Peptide record

TPDB13516

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13516
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGAVAKVLTTGAPALISWIKRKRQQ
Physicochemical Analysis
C125H216N38O32
NDCEHMFY
A
2763.33
12.43
5
0
12
+5
2.20
0.119
112.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
199.04
5
Residue Composition
number
4
A
2
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
3
I
2
L
3
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 3 L: 2 K: 3 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
26
C125H216N38O32
2763.33
12.43
+5
2.20
0.119
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
2% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Dissection of antibacterial and toxic activity of melittin: a leucine zipper motif plays a crucial role in determining its hemolytic activity but not antibacterial activity. | J Biol Chem | 2004