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Peptide record

TPDB13507

Plantaricin A Antibacterial Anticancer Antifungal Antiparasitic Quorum sensing standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13507
Plantaricin A
Antibacterial Anticancer Antifungal Antiparasitic Quorum sensing
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept EnsembleQS QSPred-FL
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KSSAYSLQMGATAIKQVKKLFKKWGW
Physicochemical Analysis
C140H222N36O34S1
RNDCEHP
K
2985.58
10.87
6
0
12
+6
-0.22
-0.423
67.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
12490
418.34
7
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
2
Q
2
G
0
H
1
I
2
L
6
K
1
M
1
F
0
P
3
S
1
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 1 L: 2 K: 6 M: 1 F: 1 P: 0 S: 3 T: 1 W: 2 Y: 1 V: 1
Chemical Descriptors
26
C140H222N36O34S1
2985.58
10.87
+6
-0.22
-0.423
Free
L
Not Available
Free
Antibacterial
Lactobacillus plantarumC11, WCFS1, V90
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against P. pentosaceus Pac 1.0 (MIC 100 nM), L. plantarum 965 (MIC 300 nM), L. casei subsp. casei NCDO 161 (MIC 250 nM), L. sake NCDO 2714 (MIC 60 nM), and L. viridescens NCDO 1655 (MIC 20 nM).
Evidence 2 Activity

Activity

Not Available
Anticancer

Target

Colorectal Cancer
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1993

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 3 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against P. pentosaceus Pac 1.0 (MIC 100 nM), L. plantarum 965 (MIC 300 nM), L. casei subsp. casei NCDO 161 (MIC 250 nM), L. sake NCDO 2714 (MIC 60 nM), and L. viridescens NCDO 1655 (MIC 20 nM).
Evidence 4 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against P. pentosaceus Pac 1.0 (MIC 100 nM), L. plantarum 965 (MIC 300 nM), L. casei subsp. casei NCDO 161 (MIC 250 nM), L. sake NCDO 2714 (MIC 60 nM), and L. viridescens NCDO 1655 (MIC 20 nM).
Evidence 5 Activity

Activity

Quorum sensing

Source & Reference

NA

Other

Active against P. pentosaceus Pac 1.0 (MIC 100 nM), L. plantarum 965 (MIC 300 nM), L. casei subsp. casei NCDO 161 (MIC 250 nM), L. sake NCDO 2714 (MIC 60 nM), and L. viridescens NCDO 1655 (MIC 20 nM).