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Peptide record

TPDB13505

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13505
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 26-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SIITMTREAKLPQLWKQIACRLYNTC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C136H226N38O37S3
DGHFV
ILT
3081.70
9.70
4
1
11
+3
1.40
-0.081
97.69
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7115
2.31
10
Residue Composition
number
2
A
2
R
1
N
0
D
2
C
1
E
2
Q
0
G
0
H
3
I
3
L
2
K
1
M
0
F
1
P
1
S
3
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 2 E: 1 Q: 2 G: 0 H: 0 I: 3 L: 3 K: 2 M: 1 F: 0 P: 1 S: 1 T: 3 W: 1 Y: 1 V: 0
Chemical Descriptors
26 reviewed residue count
C136H226N38O37S3 sequence-only estimate (linear, free termini)
3081.70 sequence-only estimate (linear, free termini)
9.70 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.40 sequence-only estimate (linear, free termini)
-0.081 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:17764786]Little hemolytic activity on red blood cells even with peptide concentration up to 200 µg/ml

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2007 Oct 28(10):2069-2074.