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Peptide record

TPDB13504

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB13504
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
KIPPVVKDTLKKVAKGVLSAVAGALS
Physicochemical Analysis
C119H213N31O32
RNCEQHMFWY
KV
2590.19
10.71
5
1
13
+4
5.18
0.569
131.15
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
4
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
1
I
3
L
5
K
0
M
0
F
2
P
2
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 5 M: 0 F: 0 P: 2 S: 2 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
26
C119H213N31O32
2590.19
10.71
+4
5.18
0.569
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>512 µM
Hemolytic Cytotoxic
50% Hemolysis | >512 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Low structural variation in the host-defense peptide repertoire of the dwarf clawed frog Hymenochirus boettgeri (Pipidae). | PLoS One | 2014