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Peptide record

TPDB13501

RFSLK Antibacterial Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13501
RFSLK
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-MDRFSLKWKKKRKIRRRRRRRRRRR-NH2
Physicochemical Analysis
C152H278N70O29S1
ANCEQGHPTYV
R
3582.39
13.14
18
1
5
+17
12.76
-2.808
31.20
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
153.53
1
Residue Composition
number
0
A
13
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
5
K
1
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 13 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 5 M: 1 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
25
C152H278N70O29S1
3582.39
13.14
+17
12.76
-2.808
Amidation
L
Linear
Acetylation
N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Escherichia Coli Strains And S. Aureus: ATCC 29213, FDA486, MRSA 43484 And FUSA 88779 S. Epidermidis: Clinical Isolates

Assay & Model

Balb/C female mice
Balb/C female mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
In vitro and in vivo
CCSSSSCHHHHTTGGGGGGGGGCCC
Additional Detail Fields 1 fields
CCSSSSCHHHHTTGGGGGGGGGCCC