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Peptide record

TPDB13497

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13497
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
AGKETIFQRLKKKIQEKGKRAKIAW
Physicochemical Analysis
C135H231N41O33
NDCHMPSYV
K
2956.57
11.23
9
2
9
+7
8.93
-1.088
74.40
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
186.03
3
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
2
E
2
Q
2
G
0
H
3
I
1
L
7
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 2 G: 2 H: 0 I: 3 L: 1 K: 7 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
25
C135H231N41O33
2956.57
11.23
+7
8.93
-1.088
Evidence Records 2 records
Evidence 1 Activity

Activity

23.4% Hemolysis
Toxicity
>16 µM
Hemolytic Cytotoxic
23.4% Hemolysis | >16 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity. | Front Microbiol | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis