Peptide record

TPDB13474

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13474
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IVKRFFRISYKLQSLKIIKGKRTFT
Physicochemical Analysis
C146H244N40O32
ANDCEHMPW
K
3071.79
12.17
8
0
11
+8
1.89
-0.120
105.20
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
48.51
6
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
4
I
2
L
5
K
0
M
3
F
0
P
2
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 4 L: 2 K: 5 M: 0 F: 3 P: 0 S: 2 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
25
C146H244N40O32
3071.79
12.17
+8
1.89
-0.120
Evidence Records 1 records
Evidence 1 Activity

Activity

88.8% Killing
Toxicity
42 µM
Cytotoxic
88.8% Killing | 42 | µM | target cell: Mouse fibroblasts McCoy

Target

Mouse fibroblasts McCoy

Source & Reference

NA
DBAASP
The Hirudo Medicinalis Microbiome Is a Source of New Antimicrobial Peptides. | Int J Mol Sci | 2020