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Peptide record

TPDB13470

Antibacterial Anticancer Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13470
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RPLNFKMLRFWGQQQCRRPLYCRRR
Physicochemical Analysis
C146H234N52O31S3
ADEHISTV
R
3309.97
12.28
8
0
8
+8
2.29
-1.252
46.80
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
7115
214.96
7
Residue Composition
number
0
A
7
R
1
N
0
D
2
C
0
E
3
Q
1
G
0
H
0
I
3
L
1
K
1
M
2
F
2
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 1 D: 0 C: 2 E: 0 Q: 3 G: 1 H: 0 I: 0 L: 3 K: 1 M: 1 F: 2 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
25
C146H234N52O31S3
3309.97
12.28
+8
2.29
-1.252
Evidence Records 2 records
Evidence 1 Activity

Activity

1.75% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
1.75% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020
Evidence 2 Activity

Activity

3.51% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
3.51% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020