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Peptide record

TPDB13465

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13465
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RKVRGPPGGGRLLRPLLQLLKQKLR
Physicochemical Analysis
C128H233N45O28
ANDCEHIMFSTWY
L
2850.54
13.01
8
0
8
+8
5.72
-0.672
120.80
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
2
Q
4
G
0
H
0
I
7
L
3
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 4 H: 0 I: 0 L: 7 K: 3 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C128H233N45O28
2850.54
13.01
+8
5.72
-0.672
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
0% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Enhancement of the antimicrobial activity and selectivity of GNU7 against Gram-negative bacteria by fusion with LPS-targeting peptide. | Peptides | 2016
Evidence 2 Activity

Activity

0% Killing
Toxicity
8 µM
Cytotoxic
0% Killing | 8 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Enhancement of the antimicrobial activity and selectivity of GNU7 against Gram-negative bacteria by fusion with LPS-targeting peptide. | Peptides | 2016