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Peptide record

TPDB13456

Antibacterial Antifungal Blood-Brain Barrier Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13456
Antibacterial Antifungal Blood-Brain Barrier Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CAFPdb dbAMP B3Pred BBPpredict pep-lab ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Blood-Brain Barrier, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
CKGKGAKCSRLMYDCCTGSCRSGKC
Physicochemical Analysis
C102H177N35O33S7
NEQHIFPWV
C
2646.16
8.89
6
1
4
+5
4.04
-0.464
19.60
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1865
70.48
11
Residue Composition
number
1
A
2
R
0
N
1
D
6
C
0
E
0
Q
4
G
0
H
0
I
1
L
4
K
1
M
0
F
0
P
3
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 6 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 1 K: 4 M: 1 F: 0 P: 0 S: 3 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
25
C102H177N35O33S7
2646.16
8.89
+5
4.04
-0.464
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
4230 µM
Hemolytic Cytotoxic
50% Hemolysis | 4230 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrocyclic Antimicrobial Peptides Engineered from ?-Conotoxin. | Curr Pharm Des | 2017