Back to search

Peptide record

TPDB13450

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13450
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
AKTNRIAKELRRYIRKVGRIARKAW
Physicochemical Analysis
C136H237N49O31
DCQHMFPS
R
3054.69
12.42
10
1
11
+9
6.52
-0.968
90.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
228.83
3
Residue Composition
number
4
A
6
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
3
I
1
L
4
K
0
M
0
F
0
P
0
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 6 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 4 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
25
C136H237N49O31
3054.69
12.42
+9
6.52
-0.968
Evidence Records 2 records
Evidence 1 Activity

Activity

14.6% Hemolysis
Toxicity
>8 µM
Hemolytic Cytotoxic
14.6% Hemolysis | >8 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity. | Front Microbiol | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis