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Peptide record

TPDB13445

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13445
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
KKKKKKAAAFAAAAAFAAWAAFAAA
Physicochemical Analysis
C119H186N32O26
RNDCEQGHILMPSTYV
A
2480.98
11.21
6
0
19
+6
-1.85
0.444
60.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
221.69
0
Residue Composition
number
15
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
6
K
0
M
3
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 15 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 6 M: 0 F: 3 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
25
C119H186N32O26
2480.98
11.21
+6
-1.85
0.444
Evidence Records 3 records
Evidence 1 Activity

Activity

17% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
17% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 2 Activity

Activity

11% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
11% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis