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Peptide record

TPDB13438

Antibacterial Hemolysis Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB13438
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
AWRESIKAYLKKEIKKKGKRIVAAW
Physicochemical Analysis
C141H234N40O32
NDCQHMFPT
K
3001.66
10.93
9
2
12
+7
5.99
-0.756
90.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
12490
416.10
2
Residue Composition
number
4
A
2
R
0
N
0
D
0
C
2
E
0
Q
1
G
0
H
3
I
1
L
7
K
0
M
0
F
0
P
1
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 7 M: 0 F: 0 P: 0 S: 1 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
25
C141H234N40O32
3001.66
10.93
+7
5.99
-0.756
Evidence Records 2 records
Evidence 1 Activity

Activity

14.4% Hemolysis
Toxicity
>32 µM
Hemolytic Cytotoxic
14.4% Hemolysis | >32 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity. | Front Microbiol | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis