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Peptide record

TPDB13426

Antibacterial standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB13426
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FFPIIARLAAKVIPSLVCAVTKKC
Physicochemical Analysis
C122H206N30O27S2
NDEQGHMWY
A
2589.28
10.32
4
0
14
+4
-0.31
1.275
134.17
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.83
4
Residue Composition
number
4
A
1
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
3
I
2
L
3
K
0
M
2
F
2
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 2 K: 3 M: 0 F: 2 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C122H206N30O27S2
2589.28
10.32
+4
-0.31
1.275
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25-49 µg/mL

Target

Streptococcus pyogenes

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 6538P (MIC 1-2/1-2 ug/ml), S. pyogenes (MIC 25-49 ug/ml), Gram- P. aeruginosa ATCC 10148 (MIC 20- >78/39 ug/ml), E. coli ATCC 9723H or ATCC 25922
Evidence 2 Activity

Activity

MIC
Antibacterial
2-6 µg/mL

Target

Escherichia coli ATCC 9723H or ATCC 25922 or MDR

Source & Reference

NA

Other

l), S. pyogenes (MIC 25-49 ug/ml), Gram- P. aeruginosa ATCC 10148 (MIC 20- >78/39 ug/ml), E. coli ATCC 9723H or ATCC 25922 or MDR (MIC 2-6 ug/ml). Updated 6/2024