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Peptide record

TPDB13424

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB13424
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LVTLVFVGGGWKWKWKNGKWKWKW
Physicochemical Analysis
C154H217N37O27
ARDCEQHIMPSY
KW
3018.65
11.21
6
0
12
+6
-6.60
-0.483
68.75
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
33000
1093.20
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
2
L
6
K
0
M
1
F
0
P
0
S
1
T
6
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 2 K: 6 M: 0 F: 1 P: 0 S: 0 T: 1 W: 6 Y: 0 V: 3
Chemical Descriptors
24
C154H217N37O27
3018.65
11.21
+6
-6.60
-0.483
Evidence Records 1 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
12% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Conversion of Broad-Spectrum Antimicrobial Peptides into Species-Specific Antimicrobials Capable of Precisely Targeting Pathogenic Bacteria. | Sci Rep | 2020