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Peptide record

TPDB13414

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB13414
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLKELWTKMKGAGKAVLGKIKGLL
Physicochemical Analysis
C122H215N31O28S1
RNDCQHFPSY
LK
2596.30
10.82
6
1
12
+5
2.12
0.287
134.17
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
211.84
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
4
G
0
H
1
I
6
L
6
K
1
M
0
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 0 I: 1 L: 6 K: 6 M: 1 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
24
C122H215N31O28S1
2596.30
10.82
+5
2.12
0.287
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
0% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Investigation of the structure-activity relationship in ponericin L1 from Neoponera goeldii. | Pept Sci (Hoboken) | 2020
Evidence 2 Activity

Activity

0.2% Hemolysis
Toxicity
2 µg/mL
Hemolytic Cytotoxic
0.2% Hemolysis | 2 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial potential of a ponericin-like peptide isolated from Bombyx mori L. hemolymph in response to Pseudomonas aeruginosa infection. | Sci Rep | 2022
Evidence 3 Activity

Activity

0% Cytotoxicity
Toxicity
2 µg/mL
Cytotoxic
0% Cytotoxicity | 2 | µg/mL | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Antimicrobial potential of a ponericin-like peptide isolated from Bombyx mori L. hemolymph in response to Pseudomonas aeruginosa infection. | Sci Rep | 2022