Back to search

Peptide record

TPDB13404

Antibacterial Antifungal Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13404
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FLPGILKVAANVVPGVICAITKKC
Physicochemical Analysis
C114H196N28O27S2
RDEQHMSWY
V
2455.10
9.80
3
0
13
+3
0.56
1.300
142.08
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
5.09
4
Residue Composition
number
3
A
0
R
1
N
0
D
2
C
0
E
0
Q
2
G
0
H
3
I
2
L
3
K
0
M
1
F
2
P
0
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 2 K: 3 M: 0 F: 1 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
24
C114H196N28O27S2
2455.10
9.80
+3
0.56
1.300
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
145.8 µM
Hemolytic Cytotoxic
50% Hemolysis | 145.8 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020
Evidence 2 Activity

Activity

75% Killing
Toxicity
0.1 µM
Cytotoxic
75% Killing | 0.1 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020