Back to search

Peptide record

TPDB13382

Antibacterial Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13382
Antibacterial Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept i2APP AI4AVP AVPpred-BWR APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
LIGLVSKGTCVLVKTVCKKVLKQ
Physicochemical Analysis
C111H205N29O28S2
ARNDEHMFPWY
KV
2458.15
10.39
5
0
10
+5
3.28
0.857
147.83
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
5.09
6
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
1
Q
2
G
0
H
1
I
4
L
5
K
0
M
0
F
0
P
1
S
2
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 4 K: 5 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 5
Chemical Descriptors
23
C111H205N29O28S2
2458.15
10.39
+5
3.28
0.857
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
<50 µM

Target

B. subtilis

Source & Reference

NA

Other

Active against E. coli and S. aureus (MIC < 25 uM), B. subtilis (MIC <50 uM), not active against P.aeruginosa, C.albicans, S.cerevisiae, and L.garvieae.
Evidence 2 Activity

Activity

MIC
Antifungal
<50 µM

Target

B. subtilis

Source & Reference

Antifungipept

Other

Active against E. coli and S. aureus (MIC < 25 uM), B. subtilis (MIC <50 uM), not active against P.aeruginosa, C.albicans, S.cerevisiae, and L.garvieae.
Evidence 3 Activity

Activity

MIC
Antiparasitic
<50 µM

Target

B. subtilis

Source & Reference

NA

Other

Active against E. coli and S. aureus (MIC < 25 uM), B. subtilis (MIC <50 uM), not active against P.aeruginosa, C.albicans, S.cerevisiae, and L.garvieae.
Evidence 4 Activity

Activity

MIC
Antiviral
<50 µM

Target

B. subtilis

Source & Reference

NA

Other

Active against E. coli and S. aureus (MIC < 25 uM), B. subtilis (MIC <50 uM), not active against P.aeruginosa, C.albicans, S.cerevisiae, and L.garvieae.
Evidence 5 Activity

Activity

50% Killing
Toxicity
0.57 µM
Cytotoxic
50% Killing | 0.57 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
2.18 µM
Hemolytic Cytotoxic
50% Hemolysis | 2.18 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 7 Activity

Activity

50% Killing
Toxicity
0.71 µM
Cytotoxic
50% Killing | 0.71 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
>12 µM
Hemolytic Cytotoxic
50% Hemolysis | >12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 9 Activity

Activity

50% Killing
Toxicity
2.34 µM
Cytotoxic
50% Killing | 2.34 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 10 Activity

Activity

50% Hemolysis
Toxicity
>10 µM
Hemolytic Cytotoxic
50% Hemolysis | >10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 11 Activity

Activity

50% Killing
Toxicity
>15 µM
Cytotoxic
50% Killing | >15 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 12 Activity

Activity

50% Hemolysis
Toxicity
>15 µM
Hemolytic Cytotoxic
50% Hemolysis | >15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 13 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.