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Peptide record

TPDB13380

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB13380
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGAVLKVLTTGLPALIKRKRQQ
Physicochemical Analysis
C111H202N34O28
NDCEHMFSWY
L
2461.04
12.43
5
0
10
+5
3.45
0.187
135.65
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
2
I
4
L
3
K
0
M
0
F
1
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
23
C111H202N34O28
2461.04
12.43
+5
3.45
0.187
Evidence Records 1 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Action mechanism of melittin-derived antimicrobial peptides, MDP1 and MDP2, de novo designed against multidrug resistant bacteria. | Amino Acids | 2018