Peptide record

TPDB13364

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB13364
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GYRTLLKKAEVKTVGKLALKHWL
Physicochemical Analysis
C125H210N34O29
NDCQIMFPS
LK
2653.25
10.76
7
1
11
+5
3.25
-0.178
118.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
263.45
3
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
1
E
0
Q
2
G
1
H
0
I
5
L
5
K
0
M
0
F
0
P
0
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 0 L: 5 K: 5 M: 0 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
23
C125H210N34O29
2653.25
10.76
+5
3.25
-0.178
Evidence Records 1 records
Evidence 1 Activity

Activity

23% Killing
Toxicity
15 µM
Cytotoxic
23% Killing | 15 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Characterization and Antimicrobial Activity of Amphiphilic Peptide AP3 and Derivative Sequences. | Antibiotics (Basel) | 2019