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Peptide record

TPDB13360

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB13360
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GWKTLLKKAEVKTVGKLALKHYL
Physicochemical Analysis
C125H210N32O29
RNDCQIMFPS
K
2625.24
10.60
7
1
11
+5
3.43
-0.152
118.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
266.26
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
1
H
0
I
5
L
6
K
0
M
0
F
0
P
0
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 0 L: 5 K: 6 M: 0 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
23
C125H210N32O29
2625.24
10.60
+5
3.43
-0.152
Evidence Records 1 records
Evidence 1 Activity

Activity

40% Killing
Toxicity
15 µM
Cytotoxic
40% Killing | 15 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Characterization and Antimicrobial Activity of Amphiphilic Peptide AP3 and Derivative Sequences. | Antibiotics (Basel) | 2019