Peptide record

TPDB13349

Antibacterial Anticancer Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13349
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QQCRRPLYCRRRKALAALAKKIL
Physicochemical Analysis
C120H215N43O27S2
NDEGHMFSTWV
R
2756.42
11.87
8
0
10
+8
3.98
-0.530
102.17
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
1615
58.59
5
Residue Composition
number
4
A
5
R
0
N
0
D
2
C
0
E
2
Q
0
G
0
H
1
I
4
L
3
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 2 G: 0 H: 0 I: 1 L: 4 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
23
C120H215N43O27S2
2756.42
11.87
+8
3.98
-0.530
Evidence Records 2 records
Evidence 1 Activity

Activity

1.75% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
1.75% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020
Evidence 2 Activity

Activity

7.02% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
7.02% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020