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Peptide record

TPDB13334

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB13334
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LRRLWLRANRLLRRLWLRANRL
Physicochemical Analysis
C132H228N50O25
DCEQGHIKMFPSTYV
RL
2915.58
13.25
8
0
12
+8
-1.20
-0.491
150.91
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11000
377.28
2
Residue Composition
number
2
A
8
R
2
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 8 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
22
C132H228N50O25
2915.58
13.25
+8
-1.20
-0.491
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
66 µM
Hemolytic Cytotoxic
50% Hemolysis | 66 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of cationic antimicrobial peptides by the tandem of leucine-rich repeat. | Amino Acids | 2013
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis