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Peptide record

TPDB13321

Antibacterial Antifungal Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB13321
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GIWKKWIKKWLKKLLKKLWKKG
Physicochemical Analysis
C144H234N36O23
ARNDCEQHMFPSTYV
K
2837.67
11.46
10
0
10
+10
-0.34
-0.873
106.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
22000
775.28
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
10
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 10 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
22
C144H234N36O23
2837.67
11.46
+10
-0.34
-0.873
Evidence Records 5 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
4.67±2.09 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 4.67±2.09 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
81.23±8.92 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 81.23±8.92 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 3 Activity

Activity

IC50
Toxicity
6.03±1.86 µg/mL
Cytotoxic
IC50 | 6.03±1.86 | µg/mL | target cell: Human vaginal epithelial cells VK2/E6E7

Target

Human vaginal epithelial cells VK2/E6E7

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 4 Activity

Activity

IC50
Toxicity
3.01±0.59 µg/mL
Cytotoxic
IC50 | 3.01±0.59 | µg/mL | target cell: Human esophagus epithelial cells Het-1A

Target

Human esophagus epithelial cells Het-1A

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis