Back to search

Peptide record

TPDB13320

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13320
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FFGHLLRGIVSVGKHIHGLITG
Physicochemical Analysis
C111H176N32O25
ANDCEQMPWY
G
2358.82
11.49
5
0
10
+2
0.27
0.791
132.73
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
5
G
3
H
3
I
3
L
1
K
0
M
2
F
0
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 3 I: 3 L: 3 K: 1 M: 0 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C111H176N32O25
2358.82
11.49
+2
0.27
0.791
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 25 uM), B. pumilus (MIC 10 uM), Psychrobacter sp. (TAD1) (MIC 2.5 uM), C. boidinii (MIC 50 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
10 µM

Target

B. pumilus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 25 uM), B. pumilus (MIC 10 uM), Psychrobacter sp. (TAD1) (MIC 2.5 uM), C. boidinii (MIC 50 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. boidinii

Source & Reference

dbAMP

Other

ainst E. coli (MIC 25 uM), B. pumilus (MIC 10 uM), Psychrobacter sp. (TAD1) (MIC 2.5 uM), C. boidinii (MIC 50 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
25 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 25 uM), B. pumilus (MIC 10 uM), Psychrobacter sp. (TAD1) (MIC 2.5 uM), C. boidinii (MIC 50 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
10 µM

Target

B. pumilus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 25 uM), B. pumilus (MIC 10 uM), Psychrobacter sp. (TAD1) (MIC 2.5 uM), C. boidinii (MIC 50 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
50 µM

Target

C. boidinii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ainst E. coli (MIC 25 uM), B. pumilus (MIC 10 uM), Psychrobacter sp. (TAD1) (MIC 2.5 uM), C. boidinii (MIC 50 uM).
Evidence 7 Activity

Activity

7% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
7% Hemolysis | 10 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Trematocine, a Novel Antimicrobial Peptide from the Antarctic Fish Trematomus bernacchii: Identification and Biological Activity. | Antibiotics (Basel) | 2020
Evidence 8 Activity

Activity

55% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
55% Hemolysis | 50 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Trematocine, a Novel Antimicrobial Peptide from the Antarctic Fish Trematomus bernacchii: Identification and Biological Activity. | Antibiotics (Basel) | 2020
Evidence 9 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human fibroblasts FB789

Target

Human fibroblasts FB789

Source & Reference

NA
DBAASP
Trematocine, a Novel Antimicrobial Peptide from the Antarctic Fish Trematomus bernacchii: Identification and Biological Activity. | Antibiotics (Basel) | 2020
Evidence 10 Activity

Activity

50% Cell death
Toxicity
50 µM
Cytotoxic
50% Cell death | 50 | µM | target cell: Human fibroblasts FB789

Target

Human fibroblasts FB789

Source & Reference

NA
DBAASP
Trematocine, a Novel Antimicrobial Peptide from the Antarctic Fish Trematomus bernacchii: Identification and Biological Activity. | Antibiotics (Basel) | 2020