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Peptide record

TPDB13309

Antibacterial Antifungal standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13309
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFCWNVAVYRNGVRVAHRRCN
Physicochemical Analysis
C107H165N39O26S2
DEQILKMPST
RV
2477.85
11.00
5
0
9
+4
1.02
-0.310
64.76
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7115
287.14
6
Residue Composition
number
2
A
4
R
3
N
0
D
2
C
0
E
0
Q
2
G
1
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 2 R: 4 N: 3 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 4
Chemical Descriptors
21
C107H165N39O26S2
2477.85
11.00
+4
1.02
-0.310
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. typhimurium ATCC14028

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
t Gram- bacteria E. coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7 (MIC 2 ug/ml), S. typhimurium ATCC14028 (MIC 8 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml),
Evidence 2 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP

Other

1515 or CICC21530 serotype O157:H7 (MIC 2 ug/ml), S. typhimurium ATCC14028 (MIC 8 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml), S. choleraesuis CVCC503 (MIC 16 ug/ml),
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP

Other

ug/ml), S. typhimurium ATCC14028 (MIC 8 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml), S. choleraesuis CVCC503 (MIC 16 ug/ml), P-aeruginosa CICC10419 or CICC21630 (MIC >64 ug/
Evidence 4 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. choleraesuis CVCC503

Source & Reference

dbAMP

Other

S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml), S. choleraesuis CVCC503 (MIC 16 ug/ml), P-aeruginosa CICC10419 or CICC21630 (MIC >64 ug/ml), Gram+ S.aureus ATCC43300 (MRSA-inac
Evidence 5 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

uginosa CICC10419 or CICC21630 (MIC >64 ug/ml), Gram+ S.aureus ATCC43300 (MRSA-inactive), S. aureus ATCC25923 (MIC 0.5 ug/ml), S. suis CVCC606 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633
Evidence 6 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. suis CVCC606

Source & Reference

dbAMP

Other

64 ug/ml), Gram+ S.aureus ATCC43300 (MRSA-inactive), S. aureus ATCC25923 (MIC 0.5 ug/ml), S. suis CVCC606 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATC
Evidence 7 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP

Other

5923 (MIC 0.5 ug/ml), S. suis CVCC606 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 2 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).
Evidence 8 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

L. ivanovii ATCC19119

Source & Reference

dbAMP

Other

6 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 2 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).
Evidence 9 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

S. typhimurium ATCC14028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
t Gram- bacteria E. coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7 (MIC 2 ug/ml), S. typhimurium ATCC14028 (MIC 8 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml),
Evidence 10 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP CAFPdb Antifungipept

Other

1515 or CICC21530 serotype O157:H7 (MIC 2 ug/ml), S. typhimurium ATCC14028 (MIC 8 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml), S. choleraesuis CVCC503 (MIC 16 ug/ml),
Evidence 11 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), S. typhimurium ATCC14028 (MIC 8 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml), S. choleraesuis CVCC503 (MIC 16 ug/ml), P-aeruginosa CICC10419 or CICC21630 (MIC >64 ug/
Evidence 12 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. choleraesuis CVCC503

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 4 ug/ml), S. choleraesuis CVCC503 (MIC 16 ug/ml), P-aeruginosa CICC10419 or CICC21630 (MIC >64 ug/ml), Gram+ S.aureus ATCC43300 (MRSA-inac
Evidence 13 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uginosa CICC10419 or CICC21630 (MIC >64 ug/ml), Gram+ S.aureus ATCC43300 (MRSA-inactive), S. aureus ATCC25923 (MIC 0.5 ug/ml), S. suis CVCC606 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633
Evidence 14 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

S. suis CVCC606

Source & Reference

dbAMP CAFPdb Antifungipept

Other

64 ug/ml), Gram+ S.aureus ATCC43300 (MRSA-inactive), S. aureus ATCC25923 (MIC 0.5 ug/ml), S. suis CVCC606 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATC
Evidence 15 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

5923 (MIC 0.5 ug/ml), S. suis CVCC606 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 2 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).
Evidence 16 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

L. ivanovii ATCC19119

Source & Reference

dbAMP CAFPdb Antifungipept

Other

6 (MIC 8 ug/ml), E. faecium CMCC1.2136 (MIC 2 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 2 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).