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Peptide record

TPDB13308

Antibacterial Antifungal standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13308
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFAWNVAVYRNGVRVAHRRAN
Physicochemical Analysis
C107H165N39O26
DCEQILKMPST
ARV
2413.73
12.40
5
0
11
+4
1.16
-0.376
74.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
289.59
4
Residue Composition
number
4
A
4
R
3
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 4 R: 4 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 4
Chemical Descriptors
21
C107H165N39O26
2413.73
12.40
+4
1.16
-0.376
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
or CICC21530 serotype O157:H7 (MIC 16-32 ug/ml), S-typhimurium ATCC14028 (MIC >64 ug/ml), S. enteritidis CVCC3377 (MIC 1 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 32->128 ug/ml), S-choleraesuis CVCC503 (MIC >64 ug
Evidence 2 Activity

Activity

MIC
Antibacterial
32->128 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP

Other

2 ug/ml), S-typhimurium ATCC14028 (MIC >64 ug/ml), S. enteritidis CVCC3377 (MIC 1 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 32->128 ug/ml), S-choleraesuis CVCC503 (MIC >64 ug/ml), P.aeruginosa CICC10419 or CICC21630 (MIC >128 ug
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

P.aeruginosa CICC10419 or CICC21630

Source & Reference

dbAMP

Other

ullorum CVCC1789 or CVCC1802 (MIC 32->128 ug/ml), S-choleraesuis CVCC503 (MIC >64 ug/ml), P.aeruginosa CICC10419 or CICC21630 (MIC >128 ug/ml), Gram+ S.aureus ATCC43300 MRSA (MIC > 64 ug/ml)(MRSA-inactive), S. aureus ATCC25923 (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

ICC21630 (MIC >128 ug/ml), Gram+ S.aureus ATCC43300 MRSA (MIC > 64 ug/ml)(MRSA-inactive), S. aureus ATCC25923 (MIC 2 ug/ml), S.suis CVCC606 (MIC >128 ug/ml), E. faecium CMCC1.2136 (MIC 16 ug/ml), and B. subtilis A
Evidence 5 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.suis CVCC606

Source & Reference

dbAMP

Other

aureus ATCC43300 MRSA (MIC > 64 ug/ml)(MRSA-inactive), S. aureus ATCC25923 (MIC 2 ug/ml), S.suis CVCC606 (MIC >128 ug/ml), E. faecium CMCC1.2136 (MIC 16 ug/ml), and B. subtilis ATCC6633 (MIC 4 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP

Other

(MIC 2 ug/ml), S.suis CVCC606 (MIC >128 ug/ml), E. faecium CMCC1.2136 (MIC 16 ug/ml), and B. subtilis ATCC6633 (MIC 4 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
1 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
or CICC21530 serotype O157:H7 (MIC 16-32 ug/ml), S-typhimurium ATCC14028 (MIC >64 ug/ml), S. enteritidis CVCC3377 (MIC 1 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 32->128 ug/ml), S-choleraesuis CVCC503 (MIC >64 ug
Evidence 8 Activity

Activity

MIC
Antifungal
32->128 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP CAFPdb Antifungipept

Other

2 ug/ml), S-typhimurium ATCC14028 (MIC >64 ug/ml), S. enteritidis CVCC3377 (MIC 1 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 32->128 ug/ml), S-choleraesuis CVCC503 (MIC >64 ug/ml), P.aeruginosa CICC10419 or CICC21630 (MIC >128 ug
Evidence 9 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

P.aeruginosa CICC10419 or CICC21630

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ullorum CVCC1789 or CVCC1802 (MIC 32->128 ug/ml), S-choleraesuis CVCC503 (MIC >64 ug/ml), P.aeruginosa CICC10419 or CICC21630 (MIC >128 ug/ml), Gram+ S.aureus ATCC43300 MRSA (MIC > 64 ug/ml)(MRSA-inactive), S. aureus ATCC25923 (MIC
Evidence 10 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ICC21630 (MIC >128 ug/ml), Gram+ S.aureus ATCC43300 MRSA (MIC > 64 ug/ml)(MRSA-inactive), S. aureus ATCC25923 (MIC 2 ug/ml), S.suis CVCC606 (MIC >128 ug/ml), E. faecium CMCC1.2136 (MIC 16 ug/ml), and B. subtilis A
Evidence 11 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

S.suis CVCC606

Source & Reference

dbAMP CAFPdb Antifungipept

Other

aureus ATCC43300 MRSA (MIC > 64 ug/ml)(MRSA-inactive), S. aureus ATCC25923 (MIC 2 ug/ml), S.suis CVCC606 (MIC >128 ug/ml), E. faecium CMCC1.2136 (MIC 16 ug/ml), and B. subtilis ATCC6633 (MIC 4 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 2 ug/ml), S.suis CVCC606 (MIC >128 ug/ml), E. faecium CMCC1.2136 (MIC 16 ug/ml), and B. subtilis ATCC6633 (MIC 4 ug/ml).