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Peptide record

TPDB13303

Antibacterial Hemolysis Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB13303
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KKKKKKKKKGGGLLALLALLA
Physicochemical Analysis
C105H200N30O22
RNDCEQHIMFPSTWYV
K
2234.93
11.41
9
0
9
+9
5.07
-0.386
125.71
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
6
L
9
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 6 K: 9 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C105H200N30O22
2234.93
11.41
+9
5.07
-0.386
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues. | Medchemcomm | 2019
Evidence 2 Activity

Activity

100% Cytotoxicity
Toxicity
100 µM
Cytotoxic
100% Cytotoxicity | 100 | µM | target cell: Human Lung Fibroblasts

Target

Human Lung Fibroblasts

Source & Reference

NA
DBAASP
Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues. | Medchemcomm | 2019
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis