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Peptide record

TPDB13297

Antibacterial Antifungal standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13297
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFCKAVCVYRNGVRVCHRRCN
Physicochemical Analysis
C101H166N38O25S4
DEQILMPSTW
RCV
2440.91
9.82
6
0
7
+5
3.13
-0.133
60.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1740
71.28
7
Residue Composition
number
1
A
4
R
2
N
0
D
4
C
0
E
0
Q
2
G
1
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 4
Chemical Descriptors
21
C101H166N38O25S4
2440.91
9.82
+5
3.13
-0.133
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. typhimurium ATCC14028

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Gram- bacteria E. coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 4 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml
Evidence 2 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP

Other

15 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 4 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml),
Evidence 3 Activity

Activity

MIC
Antibacterial
1-2 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP

Other

ug/ml), S. typhimurium ATCC14028 (MIC 4 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. choleraesuis CVCC503

Source & Reference

dbAMP

Other

. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA
Evidence 5 Activity

Activity

MIC
Antibacterial
16->16 µg/mL

Target

Pseudomonas aeruginosa CICC10419 or CICC21630

Source & Reference

dbAMP

Other

S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 1
Evidence 6 Activity

Activity

MIC
Antibacterial
0.25->16 µg/mL

Target

Staphylococcus aureus ATCC43300 MRSA or ATCC25923

Source & Reference

dbAMP

Other

uis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC663
Evidence 7 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. suis CVCC606

Source & Reference

dbAMP

Other

630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATC
Evidence 8 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP

Other

MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 8 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).
Evidence 9 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

L. ivanovii ATCC19119

Source & Reference

dbAMP

Other

(MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 8 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. typhimurium ATCC14028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Gram- bacteria E. coli CVCC195 or CVCC1515 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 4 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml
Evidence 11 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

S. enteritidis CVCC3377

Source & Reference

dbAMP CAFPdb Antifungipept

Other

15 or CICC21530 serotype O157:H7 (MIC 1.0 ug/ml), S. typhimurium ATCC14028 (MIC 4 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml),
Evidence 12 Activity

Activity

MIC
Antifungal
1-2 µg/mL

Target

S. pullorum CVCC1789 or CVCC1802

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), S. typhimurium ATCC14028 (MIC 4 ug/ml), S. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16
Evidence 13 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. choleraesuis CVCC503

Source & Reference

dbAMP CAFPdb Antifungipept

Other

. enteritidis CVCC3377 (MIC 0.5 ug/ml), S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA
Evidence 14 Activity

Activity

MIC
Antifungal
16->16 µg/mL

Target

Pseudomonas aeruginosa CICC10419 or CICC21630

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S. pullorum CVCC1789 or CVCC1802 (MIC 1-2 ug/ml), S. choleraesuis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 1
Evidence 15 Activity

Activity

MIC
Antifungal
0.25->16 µg/mL

Target

Staphylococcus aureus ATCC43300 MRSA or ATCC25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uis CVCC503 (MIC 4 ug/ml), P. aeruginosa CICC10419 or CICC21630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC663
Evidence 16 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. suis CVCC606

Source & Reference

dbAMP CAFPdb Antifungipept

Other

630 (MIC 16->16 ug/ml), Gram+ S. aureus ATCC43300 MRSA or ATCC25923 (MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATC
Evidence 17 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

B. subtilis ATCC6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 0.25->16 ug/ml), S. suis CVCC606 (MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 8 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).
Evidence 18 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

L. ivanovii ATCC19119

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 16 ug/ml), E. faecium CMCC1.2136 (MIC 8 ug/ml), B. subtilis ATCC6633 (MIC 2 ug/ml), L. ivanovii ATCC19119 (MIC 8 ug/ml), fungi C-albicans CGMCC2.2411 (MIC >16 ug/ml).