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Peptide record

TPDB13284

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB13284
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKAFAAAAAFAAWAAFAKKKK
Physicochemical Analysis
C107H166N28O22
RNDCEQGHILMPSTYV
A
2196.67
11.21
6
0
15
+6
-1.17
0.186
52.38
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
250.38
0
Residue Composition
number
11
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
6
K
0
M
3
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 11 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 6 M: 0 F: 3 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C107H166N28O22
2196.67
11.21
+6
-1.17
0.186
Evidence Records 3 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
3% Hemolysis | 200 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
1% Hemolysis | 50 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
50-200 µM
Hemolytic Cytotoxic
0% Hemolysis | 50-200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cationic hydrophobic peptides with antimicrobial activity | Antimicrob Agents Chemother | 2002