Back to search

Peptide record

TPDB13267

Antibacterial Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13267
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GLLDLLKGAGKGLLTHLASQI
Physicochemical Analysis
C96H168N26O27
RNCEMFPWYV
L
2118.55
9.88
3
1
10
+1
0.49
0.648
158.10
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
1
Q
4
G
1
H
1
I
7
L
2
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 4 H: 1 I: 1 L: 7 K: 2 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C96H168N26O27
2118.55
9.88
+1
0.49
0.648
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
62.5 µM

Target

Escherichia coli ATCC 35218

Source & Reference

NA

Other

Weakly active against E. coli ATCC 35218 (MIC 62.5 uM), but NOT antibiotic-resistant K.pneumoniae ATCC BAA-2814 (MIC >125 uM) and reference stra
Evidence 2 Activity

Activity

MIC
Antibacterial
>125 µM

Target

K.pneumoniae ATCC BAA-2814

Source & Reference

NA

Other

Weakly active against E. coli ATCC 35218 (MIC 62.5 uM), but NOT antibiotic-resistant K.pneumoniae ATCC BAA-2814 (MIC >125 uM) and reference strains of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (
Evidence 3 Activity

Activity

MIC
Antibacterial
125 µM

Target

K.pneumoniae ATCC 49472

Source & Reference

NA

Other

OT antibiotic-resistant K.pneumoniae ATCC BAA-2814 (MIC >125 uM) and reference strains of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 2
Evidence 4 Activity

Activity

MIC
Antibacterial
250 µM

Target

S.typhimurium ATCC 14028

Source & Reference

NA

Other

TCC BAA-2814 (MIC >125 uM) and reference strains of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 250 uM) and E.faecium ATCC 19434 (MIC 25
Evidence 5 Activity

Activity

MIC
Antibacterial
250 µM

Target

S.aureus ATCC 12600 or ATCC BAA-2312

Source & Reference

NA

Other

ins of K.pneumoniae ATCC 49472 (MIC 125 uM), S.typhimurium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 250 uM) and E.faecium ATCC 19434 (MIC 250 uM). Hemo.lytic HC50 >250 uM.
Evidence 6 Activity

Activity

MIC
Antibacterial
250 µM

Target

E.faecium ATCC 19434

Source & Reference

NA

Other

rium ATCC 14028 (MIC 250 uM), Gram+ S.aureus ATCC 12600 or ATCC BAA-2312 (MIC 250 uM) and E.faecium ATCC 19434 (MIC 250 uM). Hemo.lytic HC50 >250 uM.
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >250 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Peptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity. | Antibiotics (Basel) | 2020