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Peptide record

TPDB13261

Antibacterial Anticancer Antifungal Antiparasitic standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13261
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb DRAMP
standard
No
A 20-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
QYGRRCCNWGPGRRYCKRWC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C108H162N40O25S4
ADEHILMFSTV
R
2548.97
10.10
6
0
4
+6
4.00
-1.530
0.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
14230
5.58
8
Residue Composition
number
0
A
5
R
1
N
0
D
4
C
0
E
1
Q
3
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
2
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 4 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 2 Y: 2 V: 0
Chemical Descriptors
20 reviewed residue count
C108H162N40O25S4 sequence-only estimate (linear, free termini)
2548.97 sequence-only estimate (linear, free termini)
10.10 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
4.00 sequence-only estimate (linear, free termini)
-1.530 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against fungi A. longipes (50% inhibition IC50 12 ug/ml), B. cinerea (IC50 25 ug/m), C. sphaerospermum, F. culmorum (IC50 6 ug/m), P. digitatum (IC50 6 ug/m), T. viride (IC50 12 ug/m), and V. alboatrum (IC50 12 ug/m).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against fungi A. longipes (50% inhibition IC50 12 ug/ml), B. cinerea (IC50 25 ug/m), C. sphaerospermum, F. culmorum (IC50 6 ug/m), P. digitatum (IC50 6 ug/m), T. viride (IC50 12 ug/m), and V. alboatrum (IC50 12 ug/m).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against fungi A. longipes (50% inhibition IC50 12 ug/ml), B. cinerea (IC50 25 ug/m), C. sphaerospermum, F. culmorum (IC50 6 ug/m), P. digitatum (IC50 6 ug/m), T. viride (IC50 12 ug/m), and V. alboatrum (IC50 12 ug/m).