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Peptide record

TPDB13257

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13257
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKIAIITKNLKNFFIMLNII
Physicochemical Analysis
C114H195N27O25S1
RDCEQGHPSWYV
I
2376.03
11.00
4
0
12
+4
-0.28
0.855
161.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
0
R
3
N
0
D
0
C
0
E
0
Q
0
G
0
H
6
I
2
L
4
K
1
M
2
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 6 L: 2 K: 4 M: 1 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C114H195N27O25S1
2376.03
11.00
+4
-0.28
0.855
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020