Peptide record

TPDB13254

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13254
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 20-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
NFAEIFAAVNKLIKQGVVKG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C100H164N26O26
RDCHMPSTWY
AKV
2146.56
10.32
3
1
11
+2
0.11
0.495
117.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
0
R
2
N
0
D
0
C
1
E
1
Q
2
G
0
H
2
I
1
L
3
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 0 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 2 L: 1 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
20 reviewed residue count
C100H164N26O26 sequence-only estimate (linear, free termini)
2146.56 sequence-only estimate (linear, free termini)
10.32 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
0.11 sequence-only estimate (linear, free termini)
0.495 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning of novel antimicrobial peptide genes from the skin of the Chinese brown frog, Rana chensinensis. | Zoolog Sci | 2011