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Peptide record

TPDB13253

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13253
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLFGAIAGFIKKGWKGMVKG
Physicochemical Analysis
C99H157N25O21S1
RNDCEQHPSTY
G
2065.55
11.00
4
0
10
+4
-1.77
0.460
83.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
266.27
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
6
G
0
H
2
I
1
L
4
K
1
M
2
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 6 H: 0 I: 2 L: 1 K: 4 M: 1 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
20
C99H157N25O21S1
2065.55
11.00
+4
-1.77
0.460
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
195.1 µg/mL
Cytotoxic
50% Cytotoxicity | 195.1 | µg/mL | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
162.0 µg/mL
Cytotoxic
50% Cytotoxicity | 162.0 | µg/mL | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015
Evidence 3 Activity

Activity

15% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
15% Hemolysis | 250 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015
Evidence 4 Activity

Activity

<5% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015