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Peptide record

TPDB13252

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13252
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GWFKTYKDWPVIISNVPGVI
Physicochemical Analysis
C114H167N25O27
ARCEQHLM
IV
2319.73
9.65
2
1
10
+1
-1.67
0.275
102.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
538.42
4
Residue Composition
number
0
A
0
R
1
N
1
D
0
C
0
E
0
Q
2
G
0
H
3
I
0
L
2
K
0
M
1
F
2
P
1
S
1
T
2
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 0 K: 2 M: 0 F: 1 P: 2 S: 1 T: 1 W: 2 Y: 1 V: 3
Chemical Descriptors
20
C114H167N25O27
2319.73
9.65
+1
-1.67
0.275
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
0% Hemolysis | 64 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020