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Peptide record

TPDB13242

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13242
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AKAIVRTIEQAPKTAKAKKS
Physicochemical Analysis
C94H171N29O27
NDCGHLMFWY
AK
2139.57
11.10
6
1
8
+5
7.82
-0.630
78.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
5
A
1
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
2
I
0
L
5
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 2 L: 0 K: 5 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C94H171N29O27
2139.57
11.10
+5
7.82
-0.630
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020