Peptide record

TPDB13238

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13238
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKSINSLHLAMLKKQRLNRD
Physicochemical Analysis
C103H185N35O28S1
CEGFPTWYV
LK
2393.88
11.63
7
1
7
+5
6.50
-1.000
102.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
1
A
2
R
2
N
1
D
0
C
0
E
1
Q
0
G
1
H
1
I
4
L
4
K
1
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 2 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 4 K: 4 M: 1 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C103H185N35O28S1
2393.88
11.63
+5
6.50
-1.000
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020