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Peptide record

TPDB13233

Antibacterial Anticancer Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13233
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WGKFFAGVKKLTKAILAVRA
Physicochemical Analysis
C107H174N28O22
NDCEQHMPSY
AK
2204.73
11.80
5
0
12
+5
-1.15
0.540
107.50
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
249.46
1
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
2
L
4
K
0
M
2
F
0
P
0
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 4 M: 0 F: 2 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
20
C107H174N28O22
2204.73
11.80
+5
-1.15
0.540
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human dermal microvascular endothelial cells HDME

Target

Human dermal microvascular endothelial cells HDME

Source & Reference

NA
DBAASP
Rational Design of Membrane-Pore-Forming Peptides. | Small | 2017
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HDME: Not active up to 100 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Small. 2017 Oct 13(40).