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Peptide record

TPDB13231

Antibacterial Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13231
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RQYMRQIEQALRYGYRISRR
Physicochemical Analysis
C114H187N41O30S1
NDCHKFPTWV
R
2644.06
11.74
6
1
8
+5
4.36
-1.480
63.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
4470
169.06
7
Residue Composition
number
1
A
6
R
0
N
0
D
0
C
1
E
3
Q
1
G
0
H
2
I
1
L
0
K
1
M
0
F
0
P
1
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 0 C: 0 E: 1 Q: 3 G: 1 H: 0 I: 2 L: 1 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
20
C114H187N41O30S1
2644.06
11.74
+5
4.36
-1.480
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. | Nat Commun | 2018
Evidence 2 Activity

Activity

IC50
Toxicity
>200 µM
Cytotoxic
IC50 | >200 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. | Nat Commun | 2018