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Peptide record

TPDB13225

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13225
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GKHKNKGKKNGKHNGWKWWW
Physicochemical Analysis
C118H170N38O24
ARDCEQILMFPSTYV
K
2504.89
11.29
9
0
4
+7
2.75
-2.470
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
22000
878.28
3
Residue Composition
number
0
A
0
R
3
N
0
D
0
C
0
E
0
Q
4
G
2
H
0
I
0
L
7
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 2 I: 0 L: 0 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
20
C118H170N38O24
2504.89
11.29
+7
2.75
-2.470
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

diffusion assay at 100 uM: active against C. albicans ATCC 90028 (7.8 mm), E. coli ATCC 25922 (9.4 mm), S. aureus ATCC 29213 (7.2 mm).
Evidence 2 Activity

Activity

6% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
6% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of microgels as carriers of antimicrobial peptides. | J Colloid Interface Sci | 2018
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membrane interactions of microgels as carriers of antimicrobial peptides. | J Colloid Interface Sci | 2018