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Peptide record

TPDB13220

Antibacterial Antiviral Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13220
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia DRAVP 2.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and DRAVP 2.0, with an available 3D structural model.
Sequence
GLFGAIAGFIKNGWKGMIKG
Physicochemical Analysis
C98H153N25O22S1
RDCEQHPSTYV
G
2065.51
10.84
3
0
10
+3
-2.72
0.495
88.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
266.28
1
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
6
G
0
H
3
I
1
L
3
K
1
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 6 H: 0 I: 3 L: 1 K: 3 M: 1 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C98H153N25O22S1
2065.51
10.84
+3
-2.72
0.495
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
144.4 µg/mL
Cytotoxic
50% Cytotoxicity | 144.4 | µg/mL | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015
Evidence 2 Activity

Activity

18% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 250 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015
Evidence 4 Activity

Activity

50% Cytotoxicity
Toxicity
111.7 µg/mL
Cytotoxic
50% Cytotoxicity | 111.7 | µg/mL | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Antimicrobial Peptides Derived from Fusion Peptides of Influenza A Viruses, a Promising Approach to Designing Potent Antimicrobial Agents. | Chem Biol Drug Des | 2015